Effect of Nepafenac on Post-operative Macular Swelling Following Uncomplicated Cataract Surgery
Status:
Completed
Trial end date:
2008-04-01
Target enrollment:
Participant gender:
Summary
Purpose: Study the effect of nepafenac ophthalmic suspension 0.1% to prevent post-operative
cystoid macular edema following uncomplicated cataract surgery
Participants: Patients having cataract surgery at UNC who meet eligibility criteria
Procedures (methods): Patients will have pre and post-operative vision measured and optical
coherence tomography (OCT) testing, also cataract density and intraoperative
phacoemulsification parameters including ultrasound power and ultrasound time will be
measured. Patients will be randomized into two groups. Group 1 will be treated with standard
post-operative cataract management. Group 2 will be treated with standard post-operative
cataract management plus topical nepafenac for one month. Post-operative macular thickness
will be studied by analyzing the visual acuity and OCT measurements at two months post
surgery.