Overview

Effect of NSAID Use on Pain and Opioid Consumption Following Distal Radius Fracture

Status:
Recruiting
Trial end date:
2031-03-01
Target enrollment:
Participant gender:
Summary
Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are excellent medications for providing pain control in certain patients. There is some data to suggest that NSAIDs can be used to reduce postoperative pain and narcotic use in patients who had undergone carpal tunnel release. There are mixed results about the effect of bone healing in adult patients with broken bones. The investigators hypothesize that NSAID administration in the acute phase of distal radius fracture healing will be non-inferior for pain control and decrease the use of opioid analgesics compared to patients who take acetaminophen for pain control during this same time period. Furthermore, the investigators hypothesize that patients will have similar or better patient reported outcomes, range of motion, and strength with the administration of NSAIDs.
Phase:
Phase 4
Details
Lead Sponsor:
University of Missouri-Columbia
Treatments:
Acetaminophen
Anti-Inflammatory Agents, Non-Steroidal
Ibuprofen