Effect of NPH Insulin, Insulin Detemir and Insulin Glargine on GH-IGF-IGFBP Axis
Status:
Completed
Trial end date:
2012-11-01
Target enrollment:
Participant gender:
Summary
The objective is to describe the interaction of equal doses of NPH insulin (Neutral Protamine
Hagedorn), insulin Detemir and insulin glargine on IGFBP-1 (Insulin-like Growth Factor
Binding Protein-1) production as well as immunoreactive and bioactive IGF-I (Insulin-like
Growth Factor-I) after once-daily injection on three separate visits in type 1 diabetic
subjects.