Effect of N-acetylcysteine as Add on Therapy With SSRI in Moderate to Severe OCD Patients

• Status: Recruiting
• Trial end date: 2022-01-10
• Target enrollment: 0
• Participant gender: All

Summary

Title:

Effect of n-acetylcysteine as add-on therapy with Selective Serotonin Reuptake Inhibitors in moderate to severe Obsessive Compulsive Disorder patients.

Purpose of the study:

To assess the effects of the addition of n-acetylcysteine with SSRIs on the severity of symptoms in obsessive-compulsive disorder patients.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh
• Treatments: Acetylcysteine; N-monoacetylcystine

Criteria

Inclusion Criteria:

• Newly diagnosed OCD patients diagnosed by Psychiatric Consultant of the Department of Psychiatry according to DSM-5 criteria (Appendix VI).

• Moderate to severe OCD patients having AY-BOCS score > 16

• Age: 18 years or above

• Sex: Both male and female

Exclusion Criteria:

Patients receiving antidepressant within last two months.

• Patients having any history of psychiatric and medical conditions will be excluded from the study.

• Patients having suicidal thoughts.

• Pregnancy and lactation.

• Patients who are receiving psychotherapy.