Effect of N-Acetylcysteine (NAC) on Creatinine in Chronic Kidney Disease
Status:
Completed
Trial end date:
2008-10-01
Target enrollment:
Participant gender:
Summary
N-acetylcysteine is used to reduce the risk of injury to the kidney after the administration
of contrast dye. The mechanism and effectiveness of this intervention is not substantiated in
the literature. The investigators hypothesize that serum creatinine will be lower in patients
who receive NAC compared to those who receive the placebo but serum cystatin C will not
change in patients who receive NAC compared to those who receive the placebo. Also urine
creatinine will increase after the administration of NAC compared to before the
administration of NAC.