Overview

Effect of Moringa Oleifera Leaf Extract on Postoperative Pain and Bacterial Reduction in Mandibular Premolars

Status:
Not yet recruiting
Trial end date:
2023-04-01
Target enrollment:
0
Participant gender:
All
Summary
The aim of this study is to clinically compare the intensity of post-operative pain and the amount of bacterial reduction after using Moringa oleifera leaf extract solution during chemo-mechanical preparation, versus 2.5% NaOCl, in asymptomatic necrotic mandibular premolars treated in a single visit
Phase:
Phase 2/Phase 3
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Cairo University
Treatments:
Eusol
Sodium Hypochlorite
Criteria
Inclusion Criteria:

1. Systematically healthy patient (ASA I,II).

2. Age between 20 and 55 years

3. Male or female.

4. Asymptomatic mandibular premolar teeth diagnosed with pulp necrosis with apical
periodontitis.

5. Radiographic examination using Digora intraoral periapical sensor plate and software
(Digora; Soredex, Helsinki, Finland) showing mandibular premolars with (smaller than 3
mm (0-2 mm)) periapical radiolucency.

Exclusion Criteria:

1. Medically compromised patients having significant systemic disorders. (ASA III or IV).

2. History of intolerance to NSAIDS.

3. Teeth with:

- Immature roots

- Vital pulp tissues.

- Association with swelling.

- Acute peri-apical abscess or acute exacerbation of a chronic abscess.

- Mobility Grade II or III.

- Previously accessed or endodontically treated

- Deep periodontal pockets more than 4 mm

- Vertical root fractures, coronal perforation, calcification, and external or
internal root resorptions.

4. Patients who could not interpret the NRS.

5. Patients with diabetes, immune-compromising, and immunosuppression disease and
pregnant women were, also, excluded.