Effect of Montelukast on the Expression and Variation of TGF-β for Children With Mild Persistent Asthma
Status:
Completed
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
The Objective of our research is to observe the effect of cysteinyl leukotriene receptor
antagonist on the expression and variation of TGF-β1 levels and mRNA expression in children
with mild persistent asthma in their plasma and T lymphocyte, to discuss the role of TGF-β1
in the pathogenesis of bronchial asthma in children and to evaluate the function of
regulation of leukotriene receptor antagonist on asthma in children.
Details
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Collaborator:
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine