Effect of Moderate Renal Impairment and Race/Ethnicity on Treosulfan Pharmacokinetics
Status:
Not yet recruiting
Trial end date:
2024-12-01
Target enrollment:
Participant gender:
Summary
This study aim is to assess, if treosulfan pharmacokinetics are influenced by declined renal
function and by race/ethnicity of patients. The study also aims to determine an appropriate
safe dose of treosulfan, when patient's renal function is impaired. The participants of this
study are undergoing allogenic hematopoietic stem cell transplantation for treatment of acute
myeloid leukemia or myelodysplastic syndrome.