Effect of Midazolam Premedication on Mask Ventilation Difficulty

• Status: Not yet recruiting
• Trial end date: 2022-10-15
• Target enrollment: 0
• Participant gender: All

Summary

Mask ventilation has great importance during anesthesia induction because it is the only way to oxygenate patients who have lost consciousness and spontaneous breathing. Adequate muscle relaxation and depth of anesthesia may assist with mask ventilation. It is known that premedication to reduce anxiety has a relaxing effect on airway muscles. Midazolam is frequently used in premedication because it has a rapid onset of action and does not cause hemodynamic changes. In addition, midazolam may relax the airway by acting directly on the airway smooth muscle and thus facilitate mask ventilation during anesthesia induction. In this study, we will conduct a randomized controlled trial to evaluate the effect of midazolam premedication on facilitating mask ventilation in children.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Karaman Training and Research Hospital
• Treatments: Midazolam

Criteria

Inclusion Criteria:

• age 2< and <10 children

• American Society of Anesthesiologists (ASA) class I and II

• Children who are scheduled for any elective surgery under general anesthesia

Exclusion Criteria:

• age <2 or >10 years;

• obesity (body mass index, ≥35 kg/m2);

• craniofacial anomaly;

• allergic reaction to midazolam;

• presence of muscle weakness or dyspnea.

• children posted for any emergency procedure,

• above ASA class II

• children with abnormal airway anatomy,

• children with active respiratory infection in the last 3 weeks,

• children with a past history of chronic respiratory disorder,

• children who are being treated with sedative or anticonvulsive agents