Effect of Methylprednisolone on Immune Signaling in Hip-arthroplasty Patients
Status:
Completed
Trial end date:
2017-01-01
Target enrollment:
Participant gender:
Summary
The study evaluates the pathophysiological effects of a single dose Methylprednisolone
administered prior to total hip-arthroplasty (THA) surgery. The investigators examine the
effect on immune signaling and recovery after surgery.
Half of participants will receive intravenous Solu-Medrol 125 mg, while the other half will
receive placebo.
The investigators hypothesize that the group receiving Methylprednisolone will experience a
positive modulation of the immune response and an enhanced recovery.