Effect of Methylphenidate on Ecologic Function in Paediatric Acquired Brain Injury Population

• Status: Completed
• Trial end date: 2017-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to investigate the influence of Methylphenidate in pediatric acquired brain injury population, regarding ecologic (every day) function. It is hypothesized that the function with treatment will improve when compared to function without treatment in the same patient. Improvement is expected by shortening time of execution in each specific task and by reduction of the amount of assistance needed.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Loewenstein Hospital
• Treatments: Methylphenidate

Criteria

Inclusion Criteria:

1. Male and female.

2. Ages 4-18 years old.

3. No contraindications for Methylphenidate treatment such as hypersensitivity, cardiac disturbances unbalanced seizures etc'.

4. Informed consent given by their legal guardian.

5. Acquired brain injury

Exclusion Criteria:

1. Refusal to participate by either guardian or child.

2. No attentional disturbances in a computed screening exam: "TOVA".

3. Medical contraindications to treatment with Methylphenidate such as short QT syndrome.

4. Side effects due to treatment with Methylphenidate.

5. Under medical treatment of medications enhancing dopamine/ noradrenaline release such as Amantadine.

6. Unable to participate in tasks planned due to severe motor or cognitive disabilities.