Effect of Metformin on Non PCO Women Undergoing IVF/ICSI
Status:
Recruiting
Trial end date:
2020-11-27
Target enrollment:
Participant gender:
Summary
400 Patients will be randomly assigned into two groups after informed consent from every
patient.
They will be classified into 2 groups:
Group A ( involves 200 patients ) will receive metformin 850 mg twice daily along the cycle
of Intra-cytoplasmic sperm injection (ICSI) Group B ( involve 200 patients) will not receive
metformin. They will undergo a cycle of ICSI. Primary outcome of this trial is to detect
occurrence of Ovarian Hyper-stimulation Syndrome (OHSS) , while secondary outcomes include
quality & number of retrieved
follicles fertilization rate ,ongoing pregnancy rate & endometrial thickness.