The aim of this study is to investigate whether metformin has inhibitory effect on
exercise-induced lipolysis in subcutaneous adipose tissue in healthy lean man. Ten healthy
lean mean will follow protocols consisting of 60 minutes of exercise on bicycle ergometer
combined with a) orally administered metformin and b) locally administered metformin into
adipose tissue and c) without metformin treatment. Microdialysis is used for assessment of
metabolites in situ in subcutaneous adipose tissue.