Effect of Magnesium Sulphate Pretreatment in Pediatric Laparoscopy

• Status: Not yet recruiting
• Trial end date: 2024-12-01
• Target enrollment: 0
• Participant gender: All

Summary

In this study, the investigators will compare the effect of magnesium sulphate pretreatment on the onset and duration of intense and deep neuromuscular Block of rocuronium versus Cis-Atracurium and on the period of no response to nerve stimulation in children undergoing elective laparoscopic surgeries.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Assiut University
• Treatments: Atracurium; Bromides; Cisatracurium; Magnesium Sulfate; Rocuronium

Criteria

Inclusion Criteria:

1. Age group 2-12 years old

2. Both genders

3. Children who will be scheduled to undergo elective laparoscopic surgeries.

4. Patients with American Society of Anesthesiologist physical status classification of 1 or 2-

Exclusion Criteria:

1. Patients who are beyond the selected age group.

2. Patients on medications that interfered with muscle activity.

3. Allergy to medications used in this study.

4. Neuro-muscular diseases.

5. Renal or hepatic impairment.

6. Hypermagnesemia (>2.5 mmol) or hypomagnesemia (<1.7 mmol).

7. Parental refusal to participate in the study