Overview

Effect of Macugen(Pegaptanib)on Surgical Outcomes and VEGF Levels in Diabetic Patients With PDR (Diabetic Retinopathy or CSDME (Macular Edema)

Status:
Completed

Trial end date:
2008-09-01

Target enrollment:

Participant gender:

Summary

Patients with proliferative diabetic retinopathy or clinically significant diabetic macular edema requiring surgical intervention will receive a pre-operative injection of Macugen. An initial, pre-injection vitreous tap will be done in order to provide baseline VRGF 165 and cytokine levels. At the onset of the vitrectomy, a second vitreous sample will be taken to obtain intra-operative levels of Macugen, VEGF 165 and cytokines.

Phase:

N/A

Details

Lead Sponsor:

Lawson Health Research Institute

Collaborator:

Pfizer

Treatments:

Endothelial Growth Factors