Effect of Lucinactant on Mucus Clearance in Cystic Fibrosis Lung Disease
Status:
Completed
Trial end date:
2010-08-01
Target enrollment:
Participant gender:
Summary
Mucus clearance is impaired in cystic fibrosis. Inhaled surfactants may reduce adhesive
forces between mucus and airway surfaces and improve mucus clearance. This in turn my improve
lung health. The investigators propose to measure mucus clearance before and after
lucinactant or vehicle administration in patients with cystic fibrosis.
Phase:
Phase 2
Details
Lead Sponsor:
University of North Carolina, Chapel Hill
Collaborators:
Cystic Fibrosis Foundation Cystic Fibrosis Foundation Therapeutics Windtree Therapeutics