Effect of Low-dose Esketamine on Postoperative Depression in Patients With Breast Cancer
Status:
Recruiting
Trial end date:
2022-05-10
Target enrollment:
Participant gender:
Summary
esketamine is an optical isomer of ketamine. Compared with ketamine, esketamine has the
characteristics of higher effective value, stronger receptor affinity, less adverse reactions
of nervous system, and pharmacokinetics is controllable.
Domestic and foreign studies have focused on the therapeutic effect of esketamine on major
depression, but less attention has been paid to perioperative depression.This study intends
to explore the effect of small doses of esketamine on patients with breast
cancer.Postoperative depression and pain are observed.