Effect of Long Acting Anticholinergic on Nocturnal Incontinence After Radical Cystectomy and Orthotopic Neobladder
Status:
Completed
Trial end date:
2017-12-01
Target enrollment:
Participant gender:
Summary
It is a prospective randomized- placebo control crossover study to evaluate the effect of
long acting tolterodine (anticholinergic) in improving and treating nocturnal incontinence in
patient after radical cystectomy and orthotopic urinary diversion. patients will be randomly
allocated into two groups. one will receive the drug and the other will receive placebo.
continence status will be evaluated before and 4 weeks after treatment by the number of pads
used and the ICIQ-UI short form questionnaire. This is followed by two weeks of drug washout
then reevaluation of the continence status and each group will be crossed over and lastly
will be evaluated again.