Effect of Local Treatment(Carrageenan Nasal Spray and PVP-I Mouthwash) in Reducing Viral Load in Patients With COVID-19

• Status: Recruiting
• Trial end date: 2023-09-30
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this study is to recruit confirmed Covid-19 patients, to evaluate whether the topical anti-septic can improve clinical outcome in early Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) infection. During the global pandemic period, an effective and highly available method once be identified, it will reduce the risk of disease transmission and lower the medical burden.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: National Taiwan University Hospital
• Treatments: Povidone; Povidone-Iodine

Criteria

Inclusion Criteria:

1. age older than 20 years of age

2. admission with a confirmed positive test for SARS-CoV-2 infection by reverse transcription polymerase chain reaction (RT- PCR)

3. disease onset (start of COVID-19 symptom and PCR test) for ≤ 120 hours

4. available informed consent of this study.

Exclusion Criteria:

1. receiving oxygen supply before randomization

2. known intolerance/allergy to the study drugs

3. pregnancy

4. sinus/oral operation within 30 days of the beginning of the study

5. using intranasal medication before randomization

6. no available informed consent

7. inability to self-care or reply to questionnaire