Effect of Local Cannabidiol on Clinical and Inflammatory Outcomes in Periodontal Maintenance Patients.
Status:
Withdrawn
Trial end date:
2021-06-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to determine if CBD has any effect on local inflammation in
periodontal maintenance patients. This research is significant and innovative as it will act
as a pivotal study to determine if CBD is worthy of further study in the area of periodontal
disease and it will be a human clinical trial focusing on a specific aspect of periodontal
disease, the maintenance patient. Many successful therapies exist for the active, untreated
periodontal patient. Unfortunately, periodontology has not yet discovered a therapy that will
predictably treat local inflammation in these patients which are at risk for further
pocketing, bleeding on probing, bone loss and ultimately, tooth loss. Although CBD has been
patented in various forms since the 1940s, its acceptance and availability to patients has
only recently expanded exponentially. Marketing of CBD to periodontal patients as a means to
control inflammation is already commonplace online and in CBD-specific shops; it is the duty
of periodontology to determine the efficacy and success of this known anti-inflammatory
compound as it relates to clinical periodontal parameters. To determine if CBD is a
successful adjunct to conventional periodontal inflammation control therapies would be a boon
to the advancement of oral health and to millions of patients that could benefit from this
treatment.