Effect of Local Anesthesia in Patients With Marginal Periodontitis Undergoing Scaling and Root Planning

• Status: Terminated
• Trial end date: 2013-06-01
• Target enrollment: 0
• Participant gender: All

Summary

A randomised cross-over study comparing two methods of local anaesthesia for patients diagnosed with periodontitis undergoing scaling and root planning. 40 patients will be included in the study, which aims to demonstrate that the effect of a bupivacaine lozenge is non-inferior to lidocaine-adrenalin injections.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Ove Andersen
• Treatments: Bupivacaine; Epinephrine; Epinephryl borate; Lidocaine; Racepinephrine

Criteria

Inclusion Criteria:

• Patients diagnosed as having, respectively periodontitis marginalis adulta progressiva lenta and periodontitis marginalis adulta progressiva rapid in the hygiene phase, where depurations are repeated within a short timeframe

• Age between 18 and 80 years

• Ability to speak, read and understand danish

• Ability to give oral and written consent

Exclusion Criteria:

• Known allergy to bupivacaine or other local anaesthetics of the amide type

• Other gingival infections (eg lichen planus)

• Pregnancy -if in doubt a pregnancy test will be made

• Breastfeeding