Effect of Lithium Carbonate on Postoperative Sleep in Patients Undergoing Videoassisted Thoracic Surgery

• Status: Recruiting
• Trial end date: 2022-09-30
• Target enrollment: 0
• Participant gender: Male

Summary

It has been proved that lithium carbonate can prolong slow wave sleep with few or no side-effects. The aim of the present study is to evaluate postoperative sleep quality of patients undergoing video assisted thoracic surgery taken 250mg lithium carbonate 6 hours after surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: China Medical University, China
• Treatments: Calcium; Calcium Carbonate; Lithium Carbonate

Criteria

Inclusion Criteria:

• • 1. ethnic Chinese;

• • 2. age, 18 to 75 years old;

• • 3. American Society of Anaesthesiologists (ASA) physical status I or II;

• • 4. required VATS for lung surgery and one lung ventilation

Exclusion Criteria:

• Cognitive difficulties

• • Partial or complete gastrectomy

• • Previous esophageal surgery

• • Previous treated by radiotherapy or surgery

• • Inability to conform to the study's requirements

• • body mass index exceeding 30 kg/m2

• • Deprivation of a right to decide by an administrative or juridical entity

• • Ongoing participation or participation in another study <1 month ago

• • preoperative Pittsburgh Sleep Quality Index global scores higher than 6

• • recent (< 3 months prior) use of antibiotics, probiotics, prebiotics, symbiotics, hormonal medication, laxatives, proton pump inhibitors, insulin sensitizers or traditional Chinese medicine