Effect of L-Thyroxine on Lipid Profiles and Atherosclerosis in Subclinical Hypothyroidism
Status:
Active, not recruiting
Trial end date:
2022-04-01
Target enrollment:
Participant gender:
Summary
Subclinical hypothyroidism (SCH) is a common condition affecting 3-10% of the general
population, especially in women older than 50 years old. It is controversial whether SCH can
lead to increased risks of cardiovascular (CV) disease and whether treatment with L-thyroxine
reverses these risks. The present study was designed to evaluate the effect of L-thyroxine
treatment in SCH on lipid profile, atherosclerosis, endothelial function, serum inflammatory
factors and adipocytokines.