Effect of L-Dihydoxyphenylserine on Locomotion, Postural Stability, and Fall Risk Reduction in Parkinson Disease
Status:
Unknown status
Trial end date:
2019-06-01
Target enrollment:
Participant gender:
Summary
This research study is being done to determine whether treatment with L-
Dihydroxyphenylserine (L-DOPS) versus placebo (an inactive substance that looks like study
drug) in addition to other Parkinson Disease (PD) drugs will improve balance, walking, and
reduce risk of falls and/or severity of falls in PD subjects. The study is also being done to
determine the effectiveness, safety, and tolerability of L-DOPS, and whether it will decrease
Freezing of Gait (FOG), improve apathy (generalized disinterest) or show a relationship
between apathy and slowed movement and fall risk.