Overview

Effect of Ketalar to Prevent Postoperative Chronic Pain After Mastectomy

Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
0
Participant gender:
Female
Summary
Prevalence of chronic pain after mastectomy is beyond 50% 3 months after surgery. This pain is related to a sensitization of the central nervous system through N-methyl-D-asparate (NMDA) receptors. Ketalar might prevent the occurrence of chronic pain by anti-NMDA properties after mastectomy.
Phase:
Phase 4
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Hospices Civils de Lyon
Treatments:
Ketamine
Criteria
Inclusion Criteria:

- Mastectomy in patients 18 to 80 years old

Exclusion Criteria:

- American Society of Anesthesiology (ASA) class >= 3

- Renal, heart or hepatic failure

- Allergy to ketalar

- Psychiatric disease

- Chronic antalgic treatment