Effect of Isotretinoin on Immune Activation Among HIV-1 Infected Subjects With Incomplete CD4+ T Cell Recovery
Status:
Completed
Trial end date:
2016-11-01
Target enrollment:
Participant gender:
Summary
This phase II study was done in HIV-infected participants on antiretroviral therapy to
evaluate the effects of isotretinoin (a drug that is approved for use in the treatment of
severe acne) on the immune system. The immune system helps the body fight infections. When
the immune system is not working well, one may be at greater risk for diseases that are
common in aging, like heart disease, weaker bones, and kidney disease.
Phase:
Phase 2
Details
Lead Sponsor:
AIDS Clinical Trials Group
Collaborator:
National Institute of Allergy and Infectious Diseases (NIAID)