Effect of Intravenous Lidocaine on BIS-guided Propofol Requirements During General Anesthesia

• Status: Completed
• Trial end date: 2011-06-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this randomized clinical trial is to evaluate the interaction of lidocaine infusion initiated and maintained during surgery, on propofol requirements during general anesthesia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Pontificia Universidad Catolica de Chile
• Treatments: Anesthetics; Lidocaine; Propofol

Criteria

Inclusion Criteria:

• ASA I-II patients,

• Between 20 and 65 years of age

• Programed for elective laparoscopic cholecystectomy

• Eligible for total intravenous anesthesia with propofol

Exclusion Criteria:

• Unwillingness to participate in the study

• Adverse reactions to the drugs used in the study

• Use of medications that interfere in local anesthetic metabolism

• History of liver disease, kidney failure, hypoalbuminemia, hypocalcemia or hypophosphatemia

• History of drug or alcohol abuse

• Chronic use of benzodiazepines