Effect of Intrathecal Naloxone in the Incidence of Pruritis After C.S
Status:
Completed
Trial end date:
2021-03-07
Target enrollment:
Participant gender:
Summary
This randomized prospective double-blind trial will be conducted on 80 Full-term pregnant
females aged 21- 30 years presented for elective cesarean section under spinal anesthesia
where they will be randomly allocated into two equal groups:-
- Group F (40 Patients): Patients in this group will receive spinal anesthesia with 10 mg
hyperbaric bupivacaine (2 ml) plus 25 ug of fentanyl (0.5 ml).
- Group FN (40 patients): Patients in this group will receive spinal anesthesia with 10 mg
hyperbaric bupivacaine (2 ml) plus 25 ug of fentanyl (0.5 ml) plus 20 ug naloxone.
The study aim is to evaluate the effect of adding an ultra-low dose of naloxone (20 ug) to
hyperbaric bupivacaine (10 mg0 and fentanyl (25 ug) in spinal anesthesia for C.S.
Primary outcome: The incidence of pruritis Secondary outcome: The onset, the duration, the
site, and the severity of pruritis.