Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia
Status:
Unknown status
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
Many anesthesiologists use the Remifentanil for reducing a surgical pain and stabilizing a
vital sign. However, this drug induce postoperative hyperalgesia. Nowadays, many studies
report that low-dose Ketamine prevents the opioid-induces hyperalgesia. Nefopam,which is
non-opioid analgesic, has similar mechanism with Ketamine. It will be helpful for
postoperative pain control, and reduce the needs of opioid.