Overview

Effect of Intraoperative Lidocaine Infusion on Intraoperative Isoflurane Requirements

Status:
Completed
Trial end date:
2017-12-15
Target enrollment:
0
Participant gender:
All
Summary
Fifty patients were included in the study, divided into two equal groups (25 in each), underwent spinal fusion surgery.Control group: received normal saline. Lidocaine group: received lidocaine 2.0 mg/kg slowly IV before induction of anesthesia, followed by lidocaine IV infusion at a rate of 2.5 mg/kg/hr until the end of surgery. We evaluated the end-tidal isoflurane concentration required to maintain AAI index in the range of 20-25 during adult spinal fusion surgery.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
Assiut University
Treatments:
Lidocaine
Pharmaceutical Solutions
Criteria
Inclusion Criteria:

- Adult patients underwent spinal fusion surgery ASA I, II and III

Exclusion Criteria:

- History of epilepsy hearing disorders known allergy to lidocaine BMI > 35 significant
cardiac diseases significant renal diseases liver dysfunction substance abuse chronic
opioid use