Effect of Intraoperative Dexmedetomidine on Early Postoperative Cognitive Dysfunction

• Status: Completed
• Trial end date: 2019-12-01
• Target enrollment: 0
• Participant gender: All

Summary

This study will aim to identify the impact of Intraoperative dexmedetomidine infusion on POCD assessed by the Montreal Cognitive Assessment (MoCA) in geriatric patients above 60 years undergoing hip surgery under spinal anaesthesia.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Tata Main Hospital
• Treatments: Dexmedetomidine

Criteria

Inclusion Criteria:

• American society of Anesthesiology (ASA) status of I-III

• Age between 60-75 years scheduled for elective hip surgery under spinal anesthesia

Exclusion Criteria:

• Patient not willing to be a part of the study

• Patients were aged <60 or >75 years

• Patients with accompanying medical conditions that may affect the level of consciousness, such as stroke, stupor or dementia, or patients with abnormalities in hepatic or renal function, electrolyte imbalance

• Patients suffering from preoperative bradycardia [heart rate (HR) <60 bpm] or hypotension [mean arterial blood pressure (MAP) <70 mmHg]

• Patients who had recently received a sedative or opioid drug

• Patients with a MoCA (Montreal Cognitive Assessment) score <26

• Patients with persistent hypotension and bradycardia intra-operatively even after giving Mephentermine will be excluded from the study