Effect of Intranasal Neuropeptide on Emotion Perception in Trait Anxiety

• Status: Completed
• Trial end date: 2012-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to learn more about how emotional processing may be affected by a hormone called oxytocin. Oxytocin is a hormone that occurs naturally in the body, and may play an important role in the way that the brain perceives information.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Massachusetts General Hospital
• Treatments: Oxytocin

Criteria

Inclusion Criteria:

• No current Axis I according to Diagnostic & Statistical Manual for Psychiatry-IV excluded diagnoses as determined by MINI or Structured Clinical Interview for Diagnosis psychiatric diagnostic interview completed within the past 6 months

• Age 18 to 65

• Subjects must be able to give informed consent and be willing and able to comply with study procedures.

Exclusion Criteria:

• Patients with severe unstable medical illness, clinically significant laboratory findings, or serious medical illness for which hospitalization may be likely within the next three months

• Pregnant or lactating women.

• Subjects currently taking hormones, such as estrogen.

• Known hypersensitivity to oxytocin or to any of the excipients of Syntocinon Nasal spray.

• Known hyponatremia or concurrent use of diuretics.

• Subjects with a history of seizure disorder.