Overview

Effect of Intranasal Administration of Orexine A on IL-6-System, Sleep-Wake-Regulation and Neurocognition

Status:
Unknown status
Trial end date:
2009-08-01
Target enrollment:
0
Participant gender:
All
Summary
15 patients with narcolepsy and 15 healthy controls will be included in the study. According to a randomized, double-blind protocol they will receive intranasally at night first Orexine A and approximately two weeks later placebo or vice versa. Thereafter sleep will be recorded, the cytokine-system and neurocognition characterized.
Phase:
N/A
Accepts Healthy Volunteers?
Accepts Healthy Volunteers
Details
Lead Sponsor:
Zentrum für Integrative Psychiatrie
Criteria
Inclusion Criteria:

- Narcolepsy

- Age >18

- Informed consent

- GERMAN fluently spoken

Exclusion Criteria:

- Additional severe psychiatric or somatic disorders

- Pregnancy or nursing

- Anemia (Hb<10g/dl)