Overview

Effect of Ibuprofen on Postoperative Opiate Medication Use and Shoulder

Status:
Active, not recruiting
Trial end date:
2022-10-01
Target enrollment:
0
Participant gender:
All
Summary
This will be a randomized controlled trial to determine if postoperative ibuprofen after arthroscopic rotator cuff repair impacts postoperative opiate medication use, Visual Analog Scale (VAS) pain scores, shoulder range of motion (ROM), and repair integrity.
Phase:
N/A
Accepts Healthy Volunteers?
No
Details
Lead Sponsor:
University of California, San Francisco
Treatments:
Acetaminophen
Acetaminophen, hydrocodone drug combination
Hydrocodone
Ibuprofen
Oxycodone
Criteria
Inclusion Criteria:

- Patients 18 years or older

- Patients that undergo arthroscopic rotator cuff repair only

Exclusion Criteria:

- Patients less than 18 years of age, pregnant, are incarcerated. Women who are not
post-menopause are screened for pregnancy preoperatively with a urine test per our
UCSF Orthopaedic Institute preoperative guidelines.

- Patients who are unable to and not willing to comply with the study protocol and
follow-up visits

- Patients with a history of prior rotator cuff repair

- Patients with rotator cuff tears that require open repair

- Patients with an allergy to ibuprofen or anti-inflammatory medications

- Patients with a medical chart record or those who report a history of upper
gastroenterology bleed or gastic ulcers

- Patients who are currently on warfarin, enoxaparin, heparin, or a factor Xa inhibiting
anti-coagulation medication

- Patients with a known past medical history of chronic kidney disease, history of
kidney transplant, or eGFR < 60 mL/min per 1.73m2.