The investigators hypothesize that neutrophils and monocytes developed under the influence of
Interferon- gamma-1b (IFN-γ-1b, Actimmune*) in vivo will display enhanced function across a
broad range of activities related in large part to the transcriptional activation effects of
this cytokine. The investigators will evaluate the effects of IFN-γ in healthy human subjects
in vivo on gene expression, biologic activity markers, and functional activity of myeloid
cells in single dose studies and in steady state studies.