Effect of Human Plasma Protein Transfusion With and Without Crystalloids During Major Liver Resection Surgeries
Status:
Recruiting
Trial end date:
2021-09-01
Target enrollment:
Participant gender:
Summary
Evaluation of acid-base and electrolyte changes after administration of commonly used colloid
solutions (plasma protein fraction contains 5% albumin), and crystalloids (saline 0.9% and
lactated ringers solutions) is the primary endpoint of this study. The secondary endpoints
are to study dilution acidosis and changes in plasma volume induced by albumin versus
crystalloids and their effect on tissue perfusion by randomizing patients into two groups
where each group receives intraoperatively one type of the two fluids. Changes in acid-base,
electrolytes, and dilution acidosis