Effect of High Dose Vitamin D on Cancer Biomarkers and Breast Cancer Tumors
Status:
Withdrawn
Trial end date:
2024-01-01
Target enrollment:
Participant gender:
Summary
High-doses of Vitamin D (VD) may be used as targeted therapy against breast cancer. The
investigators will assess the effect of high dose VD on the following biomarkers in the
breast cancer cells: VDR, estrogen receptor (ER), progesterone receptor (PR), epidermal
growth factor receptor 2 (Her2/neu), androgen receptor (AR), as well as epidermal growth
factor receptor 1 (EGFR) and Ki-67, as markers of proliferation, and E-cadherin, a marker of
invasion and metastasis.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Eli Avisar
Treatments:
Cholecalciferol Ergocalciferols Vitamin D Vitamins