Effect of Gemcabene on the Pharmacokinetics of Atorvastatin in Healthy Volunteers

• Status: Completed
• Trial end date: 2002-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine the effect of gemcabene on the pharmacokinetics of atorvastatin 80 mg

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Gemphire Therapeutics, Inc.; NeuroBo Pharmaceuticals Inc.
• Treatments: Atorvastatin; Atorvastatin Calcium

Criteria

Inclusion Criteria:

• Males and Females

• 18-65 years of age

• Good health as determined by medical history, physical examination, vital signs, ECG, and clinical laboratory measurements;

• Body weight 45 kg or greater, with a body mass index (BMI) ≤ 35 kg/m² (weight [kg]/height[meters]²)

Exclusion Criteria:

• If female, of childbearing potential or lactation

• History of significant adverse reaction to any lipid-lowering agent