Effect of GLP-1 on Insulin-dose, Risk of Hypoglycemia and Gastric Emptying Rate in Patients With Type 1 Diabetes

• Status: Completed
• Trial end date: 2010-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The aim of the study is to investigate the effect of Victoza (a GLP-1 receptor agonist)on insulin-dose, risk of hypoglycemia and gastric emptying rate during hypoglycemia in patients with type 1 diabetes.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Hvidovre University Hospital
• Treatments: Insulin; Insulin, Globin Zinc; Liraglutide

Criteria

Inclusion Criteria:

• age 18-50y,

• BMI 18-27,

• caucasian origin,

• type 1 diabetes diagnosed between age 5 and age 40,

• no known diabetes complications or cardiovascular diseases,

• no medication known to influence glucose homeostasis,

• no pregnancy

Exclusion Criteria:

• diabetes complications,

• autonomous nerve dysfunction,

• anaemia,

• HbA1c < 8.5% at screening,

• estimated by the investigator to be incapable of completing the trial.