Effect of GLP-1 on Insulin Biosynthesis and Turnover Rates
Status:
Completed
Trial end date:
2018-07-01
Target enrollment:
Participant gender:
Summary
The gut hormone glucagon like peptide-1 (GLP-1) has been shown to have important effects on
maintaining the function and health of the insulin producing beta cells. This hormone is
known to increase the production rate of new insulin as well as increase the release of
insulin into the blood. We will measure the rate of new insulin production in subjects with
Type 2 diabetes compared to non diabetic subjects. We hypothesize that subjects with Type 2
diabetes make less insulin in response to GLP-1 compared to non diabetic subjects.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Albert Einstein College of Medicine Albert Einstein College of Medicine of Yeshiva University