Effect of GLP-1 on Glucose Metabolism in CNS Assessed by PET
Status:
Completed
Trial end date:
2011-03-01
Target enrollment:
Participant gender:
Summary
10 healthy men will be PET-scanned (CNS) twice in random order with infusions of placebo or
Native GLP-1 during hyperglycemic clamp to uncover the metabolic effects of GLP-1 in
perspectives of intervention of macrovascular late diabetic pathology such as stroke and AMI.
Earlier studies have revealed tendencies towards steady glucose metabolism in the CNS despite
fluctuations in blood sugar when infusing native GLP-1.