Overview Effect of Fluid Challenge on Glycocalyx Status: Completed Trial end date: 2018-08-01 Target enrollment: Participant gender: Summary Interventional study comparing effect of two regimes of fluid challenge in patients with sepsis and in patients undergoing elective major surgery on glycocalyx by using perfused Boundary Region in sublingual microcirculation. Phase: N/A Details Lead Sponsor: University Hospital Hradec KraloveCollaborator: University Hospital Pilsen