Effect of Fish Oil Enriched In Omega-11 Fatty Acid On Lipoprotein Metabolism In Adults
Status:
Completed
Trial end date:
2019-11-21
Target enrollment:
Participant gender:
Summary
Background:
Fish oils are known to be beneficial to health and believed to be cardio-protective. Omega-3
fatty acid is the most known fish oil available in the market. LCMUFA (long-chain
monounsaturated fatty acids) is also a fish oil but it is derived from fish that consumes a
diet rich in omega-11 fatty acid. Researchers want to study omega-11 fatty acid enriched fish
oil and understand its effect on cardiovascular health.
Objective:
To understand the effects of LCMUFA from fish oil on cardiovascular health.
Eligibility:
Healthy volunteers ages 18 and older with no history of cardiovascular disease
Design:
Participants will be screened with:
- Medical history
- Physical exam
- Fasting blood and urine tests
- Optional stool sample
- Questions about their diet, exercise, and the types of medicines and dietary supplements
they take
- 7-day food diary
- Cardio-Ankle Vascular Index (CAVI): Blood pressure is taken in the arms and legs. The
heart is monitored.
- After the screening visit, participants will take 4 gel capsules, 3 times a day after
meals, for 8-10 weeks.
- Electrocardiogram (EKG)
Participants will have 3 additional visits. All include repeats of the screening tests.
Visit 2 is 8 weeks after the screening visit. Participants will stop taking the capsules for
8 weeks after this visit.
Visit 3 is at least 16 weeks after starting the supplement. Participants will take 4
capsules, 3 times a day after meals, for 8 weeks after this visit.
Visit 4 is 8 weeks after starting the second supplement.