Effect of Fentanyl on the Rate of Anesthesia

• Status: Completed
• Trial end date: 2013-01-01
• Target enrollment: 0
• Participant gender: All

Summary

Achievement of a deep and long-durated anesthesia is vital before most endodontic procedures; therefore, the investigators conducted this study to compare the local infiltration effect of epinephrine-containing lidocaine with/ without fentanyl on depth and duration of anesthesia in maxillary molars with painful irreversible pulpitis.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Islamic Azad University, Tehran
• Treatments: Epinephrine; Epinephryl borate; Fentanyl; Lidocaine; Racepinephrine

Criteria

Inclusion Criteria:

• Patients were aged between 18 and 65 years with no systemic diseases categorized in the Class I ASA;

• Individuals requiring urgent root canal treatment of maxillary first or second molars;

• Hot painful teeth with irreversible pulpitis (moderate to severe spontaneous pain), with a positive response to thermal vitality tests (a long painful response to a cold test) and no clinical or radiographic signs or symptoms of acute or chronic apical periodontitis; and

• No history of taking analgesics in the previous 12 h.

Exclusion Criteria:

• Systemic conditions;

• Allergic reactions to opioids, benzodiazepines, barbiturates;

• Pregnancy and lactation; Contraindication of the use of epinephrine (such as unstable angina);

• Nonvital pulp after access cavity preparation