Effect of Exenatide, Sitagliptin or Glimepiride on Functional ß -Cell Mass
Status:
Completed
Trial end date:
2012-11-01
Target enrollment:
Participant gender:
Summary
This study evaluates exenatide, sitagliptin, and glimepiride for the treatment of high blood
sugar in patients with impaired fasting glucose or early type 2 diabetes. The purpose of this
study is to determine if exenatide and sitagliptin increase the amount of insulin made by the
pancreas compared to glimepiride. It is hypothesized that exenatide or sitagliptin will
sustain or increase the amount of insulin made by the pancreas in comparison to glimepiride.