Effect of Evolocumab on Coronary Endothelial Function
Status:
Completed
Trial end date:
2019-11-30
Target enrollment:
Participant gender:
Summary
The investigators propose a pilot study using (1) MRI to assess coronary artery endothelial
function, (2) brachial ultrasound to assess systemic endothelial function, (3) serum markers
of inflammation and of endothelial cell function and (4) echocardiographic measures of left
ventricular diastolic and systolic properties, before and following initiation of PCSK9
antibody in HIV positive subjects.