Effect of Eurycoma Longifolia (DLBS5055) and Multivitamins (Vitamin C+Vitamin E+ β-carotene) for Infertile Males
Status:
Recruiting
Trial end date:
2024-11-01
Target enrollment:
Participant gender:
Summary
Infertility is defined as the inability of a couple to get pregnant after one year of regular
and unprotected sexual intercourse. Although it is not a life-threatening condition,
infertile couple often suffer from mental health issues, including depression and low
self-esteem that may impact their Quality of Life (QoL). Male factors contribute to a half of
the underlying causes of infertility and semen analysis play a vital role in investigation of
the fertility status of the male partners. By performing semen analysis, we could predict the
chance of a couple to conceive.
Male infertility treatments include surgery, hormonal treatment and also assisted
reproductive techniques, such as intra uterine insemination and in vitro fertilization that
may lead to a financial burden for infertile couple. For facing this issue, traditional or
herbal medicine and antioxidants are often be used as an alternative way by many infertile
couples. One of the traditional medicines used in Indonesia and other Southeast-Asia
Countries for infertility cases is Eurycoma longifolia or Pasak Bumi.
Based on previous studies in animals, Eurycoma longifolia could improve Testosterone and may
improve sperm parameters, even though there are very few studies in human including in
Indonesia. Antioxidants (multivitamins) are also routinely given to the infertile men as they
could protect sperm damages from oxidative stress and may in advanced improve sperm quantity
and quality. Our study aims to compare the effect of Eurycoma longifolia, Multivitamins and
the combination on sperm parameters and also reproductive hormones of the infertile males.