Effect of Estrogen on Mental and Social Functioning in Girls With Turner's Syndrome

• Status: Completed
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: Female

Summary

RATIONALE: Turner's syndrome is a disease in which females are missing all or part of one X chromosome and do not produce estrogen. Giving estrogen is standard treatment for girls who have Turner's syndrome. Estrogen may be effective treatment for mental and social functioning problems experienced by girls with Turner's syndrome.

PURPOSE: Clinical trial to study the effectiveness of long term estrogen therapy on mental and social functioning in girls who have Turner's syndrome.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: National Institute of Neurological Disorders and Stroke (NINDS)
• Collaborator: Jefferson Medical College of Thomas Jefferson University
• Treatments: Estrogens

Criteria

PROTOCOL ENTRY CRITERIA:

• Girls aged 8 and 12 years with Turner's syndrome-compatible karyotype

• Age-matched girls without Turner's syndrome entered as controls

• Concurrent registration on Thomas Jefferson University growth study required of subjects with Turner's syndrome