Effect of Esmolol on Perioperative Stress Reaction

• Status: Not yet recruiting
• Trial end date: 2023-12-31
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this clinical trial is to observe the effect of low dose continuous infusion of esmolol on perioperative stress response in patients undergoing airway intervention .

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Xiumei Song
• Treatments: Esmolol

Criteria

Inclusion criteria

1. American Society of Anesthesiologists (ASA) Physical Status I to III.;

2. Body mass index (BMI): 20-30 kg/m2;

3. Elective airway intervention under general anesthesia with jet ventilation，duration of operation less than 2hs;

4. Sign informed consent for clinical trial

Exclusion criteria

1. The patient and his or her family refused to participate in the study;

2. Severe respiratory or/cardiovascular or/ neurological disease, or/ hepatic or/renal dysfunction

3. Those who are allergic to the drugs used in this study;

4. Psychiatric history or with unstable mental state;

5. Patients with atrioventricular block

6. Patients with history of asthma

7. Patients now treated with β-adrenergic receptor blockers

8. Patients participating in other clinical trial