Effect of Esketamine on Reducing Postoperative Anxiety and Depression in Adolescent Patients
Status:
Not yet recruiting
Trial end date:
2025-02-10
Target enrollment:
Participant gender:
Summary
This study intends to conduct a prospective, double-blind, randomized, controlled trial.
Adolescents aged 8-17 years old are selected as subjects. Esketamine is used as intervention
before surgery, vital signs data, serum IL-6, CRP and other inflammatory indicators are
collected during surgery, and the incidence and degree of anxiety and depression are
evaluated after surgery. To determine the effect of esketamine on reducing anxiety and
depression in adolescents after surgery, and to provide an effective clinical basis for
accelerating the rehabilitation of adolescents after surgery.